Androgel – Preparation 1% of testosterone in gel form for application to the skin, intended for replacement therapy. Currently testosterone gel is one of the most commonly prescribed drugs prescribed to patients with low levels of testosterone (hypogonadism). Androgel is manufactured by Solvay Pharmaceuticals. Androgel increases testosterone levels in the blood penetrating through the skin.

Androgenic. Endogenous androgens (mainly testosterone) secreted by the testes and the main metabolite dihydrotestosterone are responsible for the development of external and internal genital organs and secondary sexual characteristics (hair growth stimulation, deepening of the voice, development of the libido). Have a general effect on protein anabolism, development of skeletal muscle and distribution of subcutaneous fat, to reduce nitrogen excretion in urine sodium, potassium, chlorides, phosphates and water. Testosterone does not cause testicular development: it reduces the pituitary secretion of gonadotropins.

Effects of testosterone on some target organs are shown after peripheral conversion of testosterone to estradiol, which then binds to the estrogen receptor in the nuclei of cells of target organs (such as the pituitary, adipose tissue, brain, bone and testicular Leydig cells).