I take 2 capsules twice daily and within the first few days noticed incredible improvement for low thyroid. My energy level has soared and my feet no longer burn. I've used Himalaya Gugguls for 5 weeks and am so impressed with it I got my 58 year old mother on it. She says that (after 13 days of use) she feels like she's 40 years old again! You won't be disappointed!